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these changes showed up by week 3 and held at 2 months
Badger TM, Huang J, Ronis M, Lumpkin CK: Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high
Histochem Cell Biol
We previously reported that reduced levels of activated hepatocyte growth factor and the c-Met receptor tyrosine kinaseboth of which are vital for maintaining cellular redox balancecombined with increased expression of GJ proteins in hepsin-deficient mice
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