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HA-CS nanocomplexes loaded with siRNA could penetrate the rabbit vitreous, and following intravitreal injection, a reduction in laser-induced neovascularization in the rabbit retina was observed, accompanied by good tolerability, biosafety, and enhanced bioavailability [32]
By indication , the type-2 diabetes mellitus segment dominated the market with a 58% share in 2025, due to the fact that it is the largest indication of GLP-1 treatments with an extensive number of patients that have been steadily increasing because of high levels of obesity and sedentary lifestyles
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