what is more effective for weight loss semaglutide or tirzepatide vs Comparing Semaglutide & Tirzepatide: Which

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Caution should be used with GLP-1 agonists in patients with long-standing diabetes complicated by gastroparesis, as well as incompletely treated diabetic retinopathy

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Its long-term safety record is, by definition, thinner: semaglutide has been prescribed to millions and carries a large post-market safety database, while retatrutide's safety profile is still being characterized in ongoing trials