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Thiazide diuretics alone or with -blockers impair glucose metabolism in hypertensive patients with abdominal obesity
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Combining these medications raises significant concerns about cardiovascular strain, gastrointestinal side effects, and unpredictable drug interactions
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The inhibitory effect of GLP-1 on gastric emptying is dose-dependent, and the use of lower doses of GLP-1 in patients with T2DM may also be suitable for blood glucose control (141)
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