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Peptides for tendon repair often apply equally to ligament healing

Indeed, the impact of the GM on host immunity is an expanding and promising research field, recently reviewed more extensively by Zhang et al

Inflammation modulation is evident by reduced pro-inflammatory cytokine expression in injured sites, shortening the inflammatory phase of healing

While GAPDH is generally localized to the cytoplasm, its sub-cellular localization can change, particularly when modified by nitrosylation, oxidation and phosphorylation ( GAPDH serves as an important enzyme within the glycolytic pathway, thereby inhibiting its function will hinder the glycolytic process, which in turn impacts the synthesis of ATP (Zhu et al., 2021)