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PDRN (polydeoxyribonucleotide) is a DNA-derived polymer that acts as a selective adenosine A2A receptor agonist

In db/db mice, exendin-4 (EX-4) significantly suppressed the overexpression of pyroptosis-related proteinsincluding ASC, caspase-1, IL-1, and GSDMD

Normal creatinine levels are 0.5 to 1.1 mg/dL for females and 0.6 to 1.2 mg/dL for males

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Molecular bases of incretin system Synthesis and distribution of GLP-1 GLP-1, GLP-2, and glucose-dependent insulinotropic polypeptide (GIP) are the predominant gut-derived incretin hormones that lead to postprandial insulin secretion in a glucose-dependent fashion