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Uncoupling of Glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction

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GLP-1 receptor agonists modulate dopaminergic signaling by increasing dopamine--hydroxylase levels, reducing dopamine release, enhancing dopamine transporter expression, increasing dopamine turnover, and suppressing NAc projections, which attenuates phasic dopaminergic signaling and reduces consummatory behaviors (Eren-Yazicioglu et al., 2021)