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These effects are typically most pronounced during dose escalation and often diminish with continued use, though some patients experience persistent symptoms requiring dose adjustment or discontinuation

Retatrutide is an investigational peptide drug developed by Eli Lilly that acts as a triple agonist, simultaneously targeting three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

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