This results in appetite suppression, increased alertness, elevated heart rate, and raised blood pressure
Our study is likely to trigger a diversification of treatment options targeting GLP1R
Take the following steps: Immediate management during an episode: Move to a quiet, safe space if possible Practice controlled breathing: breathe in slowly through your nose for 4 counts, hold for 4, exhale through your mouth for 6 counts Use grounding techniques: focus on physical sensations (feet on floor, objects you can see, sounds you can hear) Remind yourself that panic attacks, whilst distressing, are not dangerous and will pass If symptoms include chest pain, severe breathlessness, or you're unsure whether it's a panic attack, seek immediate medical attention by calling 999 or NHS 111 for urgent but non-emergency advice If experiencing thoughts of self-harm or suicide, seek urgent help via your local crisis team, A&E, or call 999 Follow-up actions: Contact your GP or prescribing clinician within 1-2 days to discuss your symptoms
Inform patients about possible side effects and ensure they fully understand before giving their consent
1 Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a growing epidemic associated with metabolic disease ( Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), including liraglutide, exenatide, semaglutide, beinaglutide, and dulaglutide, are commonly used in clinical practice to manage blood sugar and body weight