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The rarer but more serious risks include pancreatitis, gallbladder problems (especially in patients losing weight quickly), thyroid tumor concerns based on rodent studies, and vision changes tied to worsening diabetic retinopathy

Engage in regular exercise (150 minutes per week)

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Outcomes were ascertained from routinely collected health records (e.g., registers, EHR, claims)

8 GLP-1R is expressed in model organisms and humans and is highly conserved and widely distributed in the body, 9,10 such as the pancreatic islets, central nervous system, stomach, heart, lung, liver and kidney