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JAMA 276 , 15801588 (1996)
SGLT-2i = sodium-glucose cotransporter-2 inhibitor
HGF with solvent alone (without adding peroxynitrite) was assigned as the negative control
There is no formal contraindication, but the combination may affect appetite control, blood glucose regulation, and gastrointestinal symptoms
Healthcare professionals typically initiate GLP-1 therapy at a low dose and increase gradually over several weeks
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