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Peptides with very short half-lives typically require higher daily doses administered more frequently to maintain the target plasma concentration

Their common sequence, exendin 2029, specifically inhibited CAP-induced TRPV1 activation without affecting proton-induced activation and similarly alleviated CAP-induced nociceptive behaviors

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These methods offer high sensitivity and resolution, enabling detailed analysis of metabolites and enhancing our understanding of cellular metabolic pathways and their roles in health and disease [274]