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Tumors with HRD rely on alternative DNA repair mechanisms for survival, so agents that inhibit DNA single-strand break (SSB) repair or induce more SSBs trigger genomic instability and apoptosis 34

Like BPC-157, TB-500 is scheduled for FDA advisory committee review in July 2026

Pharmacol Rev 1991;43:10942.PubMed 27

The most important thing to remember here is the conversion: 1 mg = 1000 mcg

The LEADER trial demonstrated a significant reduction in the rate of cardiovascular death, nonfatal MI, or nonfatal stroke in patients with type II diabetes treated with liraglutide