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Additionally, a preclinical study using a rabbit TB model showed that bevacizumab inhibited neovascularization, enhanced drug penetration into granulomas, improved lung pathology, and increased oxygenation, suggesting its potential to enhance the effectiveness of the current TB regimens [37]

Rapamycin (sirolimus) is a prescription compound with decades of clinical use in transplant medicine at high immunosuppressant doses

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