Deepak Bagde, CEO and Head CRO and to the entire Bion Team for their dedication, expertise, and collaborative spiritkey drivers in delivering this project to fruition
Beyond the contraindications sit the warnings that shape a real conversation: acute pancreatitis, acute gallbladder disease, hypoglycemia when combined with insulin or an insulin secretagogue, acute kidney injury from volume depletion, severe gastrointestinal reactions with a specific note that the drug is not recommended in severe gastroparesis, diabetic retinopathy complications in type 2 diabetes, increases in resting heart rate, and rare reports of pulmonary aspiration during general anesthesia or deep sedation
There was also a really great group in Germany led by Michael Nauck who were doing some of the early clinical studies
Each of these scenarios degrades the peptide structure, reducing potency or destroying the medication entirely
Urine albumin as a biomarker in acute kidney injury