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Therefore, combined with the antioxidant stress effect of GPX3 and its high expression in kidney tissue, it may provide new therapeutic targets for studying kidney damage in the future

3 Therapeutic strategies targeting oxidative stress 3.1 Exogenous antioxidant supplementation Direct administration of exogenous antioxidants, while intuitively appealing, is a significant component of the unmet promise in MIRI

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Particularly noteworthy is that FOXO4 influences not only lifespan but also the quality of aging through its interaction with the protein p53commonly referred to as the "guardian of the genome." This interaction regulates whether cells remain in a senescent, metabolically inactive state or undergo programmed cell death (apoptosis)

With the January 2026 acquisition of Legacy Bank & Trust, Southern Bancorp today serves customers through 66 banking locations in Arkansas, Mississippi, Missouri, Oklahoma, and Texas