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The prespecified selection criteria included: (1) RCTs reporting desired cardiovascular or renal outcomes
1v,w and Extended Data Fig
Semaglutide binds to albumin (a protein in the blood), which protects it from rapid degradation and extends its presence in the circulation
In clinical trials, patients using Tirzepatide experienced substantial reductions in body weightoften surpassing the results seen with Semaglutide
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