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It is the predominant intracellular non-protein thiol in mammalian tissues, present at concentrations typically ranging from 110 mM in the cytosol, with particularly high concentrations in the liver (up to 10 mM), which is the primary site of GSH synthesis and export

This study established the feasibility of LCMS/MS as a confirmatory platform for NMR-based biomarker discovery

Endocrine protection of ischemic myocardium by FGF21 from the liver and adipose tissue

The report noted no adverse biochemical changes, but an uncontrolled open-label design with no comparator cannot establish a safety profile [4]