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This means its made in the neuronal cells in the brain and released in the hypothalamus, which controls several metabolic and cardiovascular functions
GLP-1-RA such as liraglutide [4], semaglutide [5], and the dual agonist tirzepatide [6], activating both the GLP1- and the gastric-inhibitory polypeptide receptor (GIP-R), have been shown to significantly reduce body weight, making them a promising therapeutic option for the treatment of obesity
Whilst standard therapeutic doses of semaglutide or liraglutide are carefully calibrated through extensive clinical trials, microdosing involves using a fraction of these established dosesoften below licensed starting doses
The Food and Drug Administration approved Ozempic to be used to lessen the risk of kidney disease from getting worse, end-stage kidney disease and cardiovascular disease-caused death for patients with type 2 diabetes and chronic kidney disease
GLP-1 treatment can also positively impact people with poor control of their blood sugar, blood pressure, and/or cholesterol levels, contributing to improved long-term health outcomes
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