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HFpEF is commonly associated with cardiovascular comorbidities such as atrial fibrillation, coronary artery disease, and chronic kidney disease, as well as non-cardiovascular conditions, including thyroid dysfunction and chronic obstructive pulmonary disease [2]
Studies of this kind must be regarded as tentative, however, as there were not adequate controls in the study including a lack of randomization, double-blinding, or placebo
Maria P
Stability of GSH under large input fluctuations Hepatocytes are seldom at steady state [21] because they receive large protein inputs during and shortly after meals and relatively little protein input between meals
Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are alternatives but should be used cautiously in patients with cardiovascular disease, kidney impairment, history of GI ulcers, or those taking anticoagulants
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