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Examples of neural tube defects include: spina bifida where the baby's spine does not develop properly anencephaly where a baby is born without parts of the brain and skull encephalocele where a membrane or skin-covered sac containing part of the brain pushes out of a hole in the skull Effects of nitrous oxide Nitrous oxide, commonly known as gas and air, is a type of anaesthetic used in dental treatments and childbirth

First level of interactions included direct interactors of analyzed nodes, while secondary interactions included first level interactions and all of their neighbors (Table 1)

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