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It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, which means it acts on two different hormonal pathways to help regulate blood sugar levels and confer additional metabolic benefits, including weight loss
These risks in humans are unknown, but retatrutide is contraindicated for individuals with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Cabungcal JH, Counotte DS, Lewis E, Tajeda HA, Piantadosi P, Pollock C, et al
(2015) 13:e1002202
Hyperglycemia frequently has been present for years before the disease was diagnosed
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