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Mycopathologia 178, 189195
Pain and sleep are metabolic: Chronic pain and poor sleep increase hunger hormones like ghrelin and disrupt repair processes, worsening metabolic dysfunction unless directly addressed
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The process might be attributed to the activation of osteoblasts (Henry & Bordoni 2022), which increased bone formation indicators such as BALP and OCN, resulting in Ca 2+ mineralization in the bone matrix
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