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Studies on skin permeation (PMID: 39795193) have investigated liposomal formulations for delivering GHK-Cu to skin tissue, measuring antiaging effects on skin architecture

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Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function

The concentrations of Interleukin-1 (IL-1), Interleukin-6 (IL-6), Tumor necrosis factor-alpha (TNF-), and Monocyte chemoattractant protein-1 (MCP-1) were quantified utilizing commercial ELISA kits (ELK Biotechnology, Wuhan, China)