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Peritoneal fluid and follicular fluid are the external microenvironments for oocyte maturation and blastocyst formation, and these abnormal microenvironments affected by iron overload may lead to impaired reproductive function.In recent years, studies on the role and mechanism of iron overload and ferroptosis in endometriosis-related infertility have been reported successively (Table 1)

A T/C polymorphism in the GPX4 3UTR affects the selenoprotein expression pattern and cell viability in transfected Caco-2 cells

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It targets adipose tissue, stimulating the breakdown of stored fat (lipolysis) and preventing the formation of new fat (lipogenesis) within adipocytes