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The effects of hyperlipidemia on glucose homeostasis may in part be mediated by this receptor (198, 199)

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Retatrutides ~24.2% (48 wk, 12 mg monotherapy) and cagrilintides ~10.8% (26 wk, 4.5 mg monotherapy) differ in duration and dose, and cagrilintides strongest data are combination (CagriSema) data

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IV administration can deliver doses up to 10 times higher than oral supplements

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The Weibull distribution model demonstrated that upper limits of 95% CIs of were all below 1 (Table S6), consistent with an early failure profile, indicating NAEs predominantly manifest during initial treatment phases

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