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demonstrated that administration of AC3174, an exenatide analog, to a high-trans-fat, high-fructose, high-cholesterol diet (HTFD)-induced NASH mouse model led to a reduction in body weight and fat mass as well as in liver and serum lipid levels and to improvement in hepatic steatosis and inflammation [8]
10.1104/pp.109.3.1047 40 FryerM
The margin between an effective stack and a wasted one comes down to understanding the specific dosage protocols, titration timing, and how these two compounds interact at the receptor level
Peptide response varies substantially across species, and no established therapeutic dosing guidelines exist outside research contexts
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