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Most clinicians suggest taking oral medications at least one hour before eating when on GLP-1 agonists, and separating important oral medications from the tirzepatide injection day is not necessary since tirzepatide effects on gastric emptying are continuous throughout the week rather than acute on injection day
As the chart shows, GLP-1s can only be prescribed for chronic weight management associated solely with obesity or a combination of obesity and glycemic control in people with type 2 diabetes
This could theoretically oppose tirzepatide's glucose-lowering effects