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Trial data indicate that tirzepatide recipients lost an average of 50.3 lb (20.2%), compared with 33.1 lb (13.7%) for those on semaglutide
Notably, ligand-activated AhR may also antagonize TGF-1 and collagen expression, suggesting that AhR may have dual roles in CKD
Oral semaglutide demonstrates similar efficacy at higher doses but requires fasting conditions and specific dosing protocols
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