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1 Beyond the weight-loss stress response, researchers have proposed several contributing mechanisms: Hormonal shifts , changes in insulin and insulin-like growth factor (IGF-1) signaling during rapid weight loss, may influence androgen activity and accelerate androgenetic alopecia in genetically predisposed patients
It adds another layer for researchers studying energy-balance and broader metabolic signalling
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The data we have comes largely from comparing separate trial populations, which introduces variables like differences in baseline BMI, diet and exercise protocols, and participant demographics
They function by enhancing insulin production, reducing appetite, and delaying gastric emptying, which collectively aids in effective weight management
