The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking
DOI: 10.1002/ctm2.1232 [Google Scholar] Pattison LA, Rickman RH, Hilton H, Dannawi M, Wijesinghe SN, Ladds G, et al
Focus on ferroptosis, pyroptosis, apoptosis and autophagy of vascular endothelial cells to the strategic targets for the treatment of atherosclerosis
doi:10.1210/clinem/dgaa863
This pricing clarity leads us to the practical question of whether TeleSlim can provide affordable access, which the next subsection answers directly