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62 Immunotherapy resistance Although immune checkpoint blockade (ICB) therapies (e.g., anti-PD-1/PD-L1, anti-CTLA-4 antibodies) have revolutionized cancer treatment, both primary and acquired resistance remain major challenges (Fig

No lethal dose has been established for BPC-157 in animal models, and it demonstrates consistent protection against drug-induced and surgical organ damage. Perovic, D

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Pernicious anaemia is often associated with other autoimmune disorders such as autoimmune thyroid disease, adrenal insufficiency, Type 1 diabetes mellitus, coeliac disease and vitiligo

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