The cells were cultured in Eagles minimum essential medium (ThermoFisher Scientific) or DMEM F-12 (ThermoFisher Scientific) respectively, supplemented with 10% Fetal Bovine Serum (Gibco) and 1% penicillinstreptomycin (ThermoFisher Scientific), in a humidified incubator maintaining 5% CO 2 at 37 C
doi:10.1196/annals.1320.015 Aufmkolk M, Ingbar JC, Kubota K, Amir SM, Ingbar SH
The prevalence of complications associated with obesity, including dyslipidaemia, hypertension, fatty liver disease and psychosocial complications are becoming increasingly prevalent within the paediatric populations
CONCLUSIONS GLP-1 RAs and multi-agonist therapies combining GLP-1 with GIP and/or GCG agonism embody transformative therapeutic approaches for MASLD/MASH, addressing multiple pathogenic pathways through complementary mechanisms of action
Outcomes: AUD diagnosis and/or alcohol-related hospitalization, preferentially reported as hazard ratios (HRs) with 95% confidence intervals (CIs)