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For mitochondrial proteomics, mitochondria were rapidly immunopurified from HeLa cells expressing a mitotag (3xHA-OMP25-mCherry) grown in indicated cell culture conditions, according to the rapid mitochondrial purification for metabolite profiling protocol
In this Perspective, we summarize the advantages and shortcomings of different sources of big data for the study of irAEs and highlight progress made using such data to identify biomarkers of irAE risk, evaluate associations between irAEs and therapeutic efficacy, and characterize the effects of demographic and anthropometric factors on irAE risk
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95% CI 1.011.26) with DPP-4 inhibitors compared with placebo [36]
Consistency Over Intensity The question of "morning vs
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