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45,46 These results were confirmed by a pooled analysis that demonstrated that the improvement in quality of life and functional capacity may be primarily related to weight loss, and that there were significant declines in HF hospitalisations or urgent visits (8 [1%] versus 30 [5%] patients in the semaglutide and placebo groups, respectively
In contrast, the sparse Japanese studies were single-center trials [7], and no study has utilized both the NP-test and monitoring of ammonia levels during carnitine treatment
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