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they do not demonstrate benefit
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Directly, at the pancreas: GLP-1 medications enhance glucose-dependent insulin secretion and suppress glucagon, improving glycemic control without forcing insulin spikes the way a sulfonylurea does
Diabetes: Often long-term
By eliminating the barrier of injection, oral semaglutide has the potential to be more frequently used early in the course of disease, and perhaps will become the preferred agent in the class. [gap]
The placebo group used in this test regained their excess weight [1]
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