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titrate +2 mg every 4 weeks CJC-1295 (No DAC) Loading 100 mcg (weeks 1-2) Frequency 1-2x daily Maintenance 100-200 mcg, 1-2x daily Route SubQ

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These guidelines, however, do not give a preference regarding which of the second-line agentswhich also include sulfonylureas (SU), dipeptidyl peptidase-4 inhibitors (DPP-IV), sodium-glucose cotransporter 2 inhibitors (SGLT-2i), insulin, thiazolidinediones (TZD) and acarboseshould be added to optimised metformin [13, 14]

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