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The compound upregulates miR-200c-3p and miR-125b-5p by two- or three-fold, suppressing mesenchymal markers and inducing apoptosis through the modulation of the Bcl-2/Bax ratio modulation (Figure 3)

Similarly, proline plays a critical role in plant defense under stress conditions by functioning as a singlet oxygen quencher, osmoregulator, and metal chelator, thereby protecting plant cell membranes and enzymes 74

Annu Rev Nutr 10:2139 Gannon JM, Forrest PE, Chengappa KR (2014) Subtle changes in thyroid indices during a placebo-controlled study of an extract of Withania somnifera in persons with bipolar disorder

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It typically takes six weeks to three months to see improvements