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The two functional tests are: Firstly, methylmalonic acid (MMA)

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SAM, SAH, and Methylation-Balance Considerations NNMT uses SAM as a methyl donor and generates SAH, so NNMT activity is directly connected to the balance between methyl-donor availability and methylation-product accumulation

Drug Categories Experimental metabolic modulator, NNMT inhibitor, anti-obesity agent, muscle regenerative enhancer

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