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Methods All mouse experiments were approved by the Animal Ethical and Welfare Committee of the Sixth Affiliated Hospital of Sun Yat-sen University carried out following their legal requirements
For eWAT and iWAT samples, a piece of tissue was chopped with scissors in ice-cold lysis buffer and homogenized passing the lysate through a 23G syringe 510 times
Some changes are harmless, while others are a sign of disease: Eating a lot of asparagus can make the urine smell like rotting cabbage
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