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PMS is a rare tumor with benign course and up to 10% are associated with malignant potential

Those with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasias should not use these drugs

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Back Elrick, H., Stimmler, L, Arai, Y (1964) 'Plasma insulin response to oral and intravenous glucose administration', Journal Clinical Endocrinology Metabolism , 24/10, 107682