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First, overexpression of the alsin long isoform protects against motor neuron toxicity induced by expression of A4T, or mutant SOD1 G85R or SOD1 G93A (Kanekura et al., 2004)
Einhorn D, Reaven GM, Cobin RH, Ford E, Ganda OP, Handelsman Y, Hellman R, Jellinger PS, Kendall D, Krauss RM, Neufeld ND, Petak SM, Rodbard HW, Seibel JA, Smith DA, Wilson PW
Other recognized side effects include injection site reactions (for subcutaneous formulations like Ozempic and Wegovy), fatigue, dizziness, and headache
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