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Overall prescribing rates (GLP-1 RA prescriptions per total prescriptions) increased throughout the first quarter of 2024 (+20.9% increase in March 2024 compared to December 2023)
Supercritical fluid extraction of emulsions (SFEE) has enabled the production of exenatide-loaded PLGA microspheres with narrow size distributions and prolonged release over 30 days, maintaining neutral internal pH to prevent peptide degradation [133]
Findings of studies involving the encapsulation of dopaminergic agents (dopamine, levodopa), dopamine agonists (ropinirole, pramipexole, bromocriptine), enzyme inhibitors (MAO-B and COMT inhibitors), HDAC6 inhibitors, and metabolic regulators (metformin) within PLGA nanoparticles are summarized
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