fda warning letters compounded semaglutide november 2025 sends letter after Chinese supplier breaks GLP-1 import restrictions FDA cracks down on 'misleading'

Compounded products may still be legally prescribed, and your healthcare provider may issue you a prescription for compounded medications based on your medical consultation

Rder, M

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Single-nucleus RNA-sequencing shows opposing effects of GIPR agonism and antagonism in the hindbrain, with antagonism, but not agonism, mimicking GLP-1R signalling and with GIPR antagonism and GLP-1R agonism both regulating gene programmes implicated in synaptic plasticity

Not a mild one, but fairly significant