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If TRIUMPH-1 confirms 25-30% weight loss in the general obesity population (not just osteoarthritis patients), Lilly has a strong argument for premium pricing
Neither is strictly better, it depends on the individual
How to avoid losing muscle while on a GLP-1 medication There are two main things you can do to minimize muscle loss: Eat enough protein throughout the day Regularly exercise Performing some type of resistance training like weightlifting is especially good, since it has a muscle-building effect
Hypoglycaemia represents a significant risk, particularly for patients on combination therapy with insulin or sulphonylureas
Overweight adults with T2D who receive either semaglutide or standard glucose-lowering therapy (sitagliptin, empagliflozin, glipizide) Overweight adults without T2D who receive either semaglutide or usual anti-obesity drugs (Contrave, phentermine, Qsymia) The objective was to evaluate the risk of skeletal outcomes such as osteoporosis, osteoarthritis (hip and knee), gout, and other bone density disorders
