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Two features set the pace observed in trials: Long half-life
Deficiency Those most at risk for developing a vitamin B-12 deficiency are vegetarians -- because the vitamin is found in dairy and meat -- and individuals with absorption problems presented by weight-loss surgery, Crohn's disease and celiac disease
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Because efficacy estimates were derived from intention-to-treat analyses, which account for non-adherence, we only applied the reduction in adherence to the price of the medications, not their efficacy
Your baseline metabolic rate, insulin resistance severity, genetic factors, and hormonal profile all affect treatment response
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