Medical history includes: morbid obesity, Charcot-Marie-Toothe, cholecystitis, alcoholism, liver failure, alcohol induced hepatitis, pancreatitis, gastrointestinal bleed at the duodenum requiring packed red blood cell, platelet, and albumin transfusion, mild varices of the esophagus and stomach, osteomyelitis of the right distal fibula, talus, tarsals, and metatarsals
The goal isnt just to help you lose weight while youre taking medication
This depends on how well the body responds and what it needs
Guidelines have evolved considerably from routine medication cessation in 2023 to GLP-1 RA continuation with individualised risk assessment in 20242025, illustrating increasing acknowledgment that certain theoretical risks may be underestimated
The following antibodies were used for western blot: anti-FXR (1:1000, Abcam, ab235094), anti-CYP7A1 (1:1000, Abcam, ab65596), anti-CYP8B1 (1:1000, Abcam, ab191910), anti-GAPDH (1:1000, Proteintech, 60004-1-Ig)