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Phase 2 dose-finding trial (Lancet 2021) showed clear dose-response from 0.3 mg up to 4.5 mg/week, but 2.4 mg is the dose Novo Nordisk advanced into Phase 3 and is the most commonly self-reported community ceiling
That's where platforms like Smytten come in handy, letting you trial different formulations before committing to full-size purchases
BMJ Open
It spreads smoothly and absorbs well, leaving the skin soft and comfortable
Pigment International, June 2017, pages 3-6 5
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