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doi: 10.1016/bs.acr.2024.04.001 86 LeeJRohJL

The phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023) provides the most detailed data available on retatrutide fatigue

and a once-weekly subcutaneous tri-agonist 4

If you are weighing mazdutide vs tirzepatide , phentermine vs semaglutide , or combining phentermine with tirzepatide , pharmacokinetic duration should factor into your decision