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F.LeiH.et al (2016)

For tesamorelin, the visceral-fat trials also reported improvements in lipid parameters lower triglycerides and an improved total-to-HDL cholesterol ratio alongside the VAT reduction

Notably, as these studies were largely open-label with varying intensities of lifestyle intervention and control conditions, they are better suited as evidence for strategic feasibility rather than as direct equivalents to placebo-controlled trials

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Tirzepatide, a dual GIP/GLP-1 receptor agonist, has demonstrated a greater reduction in HbA1c (up to 2.4%) than conventional GLP-1 agonists [4]